Explore the full depth of host–microbe interactions from RNA-seq data.
MTD Explorer is an extended and actively developed implementation of the original Meta-Transcriptome Detector (MTD). It preserves the integrated analysis of host and microbial transcriptomes while adding expanded single-end and paired-end support, exploratory and comparison modes, custom host references and functional annotations, reusable installation caches, validation tools, and updated reporting.
Original MTD:
Wu, F., Liu, Y.-Z., & Ling, B. (2022).
MTD: a unique pipeline for host and meta-transcriptome joint and
integrative analyses of RNA-seq data
.
Briefings in Bioinformatics, 23(3), bbac111.
View article
Original repository
Workflow overview
From raw reads to biological insights in five simple steps.
1. Input data
RNA-seq reads and metadata
1. Input data
RNA-seq reads and metadata
2. Process
Align, assemble & quantify
2. Process
Align, assemble & quantify
3. Explore
Browse results & visualize
3. Explore
Browse results & visualize
4. Integrate
Combine host, microbe & function
4. Integrate
Combine host, microbe & function
5. Interpret
Draw conclusions & generate insights
5. Interpret
Draw conclusions & generate insights